IARC's mission is to coordinate and conduct research on the causes of human cancer, the mechanisms of carcinogenesis, and to develop scientific strategies for cancer prevention and control. The Agency is involved in both epidemiological and laboratory research and disseminates scientific information through publications, meetings, courses, and fellowships.
09/05/2012 - Worldwide, 2 million (16.1%) of the total 12.7 million new cancer cases in 2008 are attributable to infections. This fraction is higher in less developed countries (22.9%) than in more developed countries (7.4%) and varies 10-fold by region from 3.3% in Australia and New Zealand to 32.7% in sub-Saharan Africa, according to a landmark study of infection-related cancers published today in The Lancet Oncology.
Global burden of cancers attributable to infections in 2008: a review and synthetic analysis.
C de Martel, J Ferlay, S Franceschi, J Vignat, F Bray, D Forman, M Plummer.
Lancet Oncology, Published online May 9, 2012 DOI:10.1016/S1470-2045(12)70137-7 Read more , Read article
24/04/2012 - At the initiative of the International Agency for Research on Cancer (IARC), leaders of national cancer centres from 16 Latin American countries and representatives of regional and international partners met in Lyon on 26 and 27 March 2012, to discuss the current status of research on cancer prevention and control in the region and propose avenues for progress. After the meeting, the participants formulated a statement of initiatives across the continent, spanning cancer registration, research on cancer etiology, screening and immunization, as well as education and training of cancer research scientists. These initiatives should maximize the effectiveness of the Agency’s research strategy, through their alignment and integration with the needs and priorities for cancer prevention and control in Latin America. Read statement
18/04/2012 - Currently, only about 30% of the familial risk of breast cancer has been explained, leaving the substantial majority still unaccounted for. In a large collaborative study led by Professor Melissa Southey at the University of Melbourne and Associate Professor Sean Tavtigian and Professor David Goldgar at the University of Utah, we found that mutations in a gene called XRCC2, although rare, explain another proportion of breast cancers that run in families where there is no known genetic cause and that particularly occur at an early age.
Rare Mutations in XRCC2 Increase the Risk of Breast Cancer
D.J. Park, F. Lesueur, T. Nguyen-Dumont, M. Pertesi, F. Odefrey, F. Hammet, S.L. Neuhausen, E.M. John, I.L. Andrulis, M.B. Terry, M. Daly, S. Buys, F. Le Calvez-Kelm, A. Lonie, B.J. Pope, H. Tsimiklis, C. Voegele, F.M. Hilbers, N. Hoogerbrugge, A. Barroso, A. Osorio, the Breast Cancer Family Registry, the Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer, G.G. Giles, P. Devilee, J. Benitez, J.L. Hopper, S.V. Tavtigian, D.E. Goldgar, M.C. Southey.
The American Journal of Human Genetics, Volume 90, Issue 4, 734-739, 29 March 2012. doi:10.1016/j.ajhg.2012.02.027 Read more , Read article
